Del4414_GYP5

(YPL249C)

GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication (From theSaccharomyces Genome Database)

MAT	SD5276b: a/alpha	SD5276b2: a/alpha
Aneuploidies/GCR	SD5276b	SD5276b2	Chromosome ploidy SD5276b SD5276b2 chr1 2.00 2.00 chr2 2.00 2.00 chr3 2.00 2.00 chr4 2.00 2.00 chr5 2.00 2.00 chr6 2.00 1.80 chr7 2.00 2.00 chr8 2.00 2.00 chr9 2.00 2.00 chr10 2.00 2.00 chr11 2.00 2.00 chr12 2.00 2.00 chr13 2.00 2.00 chr14 2.00 2.00 chr15 2.00 2.00 chr16 2.00 2.00
Locus Snapshot	SD5276b	SD5276b2
	SD5276b	SD5276b2
Secondary mutations	Homozygous - - - Heterozygous - - -	Homozygous - - - Heterozygous IV 163633 YDL166C FAP7 A137V X 235566 YJL101C GSH1 C264F XVI 269018 YPL150W S277:G>T:3